Cortisol CalmCortisol Calm is designed to maintain healthy cortisol levels and support relaxation, restful sleep and positive mood during times of occasional stress.* Helps maintain healthy cortisol levels under mild stress* Potential to support healthy sleep, positive mood and cognitive function* May help calm the nervous system* Made with hypoallergenic, vegetarian ingredients Cortisol, released in response to stress, is mainly produced by the adrenal cortex.